XENOBIOTIC FACTORS AFFECTING HUMAN SOMATIC AND DENTAL HEALTH

Abstract

The subject of the study was xenobiotic factors affecting human somatic and dental health. Xenobiotics, by definition, are any products of human industrial activity that pollute the environment. Purpose of the study: To study the cytopathogenic effects of xenobiotics in pediatric dentistry; especially for developing and actively growing tissues of the maxillofacial region of a child, any concentrations and doses of harmful substances are dangerous. The high sensitivity of the child's body to xenobiotics is due to the presence of critical periods in the development of organs and tissues, and the peculiarities of processes in the growing body. Heavy metals entering the body from air, water, and food can also have a significant negative impact on human health. Research methods: The article contains an analysis and review of the literature on the topic: of the influence of xenobiotic factors on the human body in general and on the condition of the oral cavity in particular. The research results showed that the dental morbidity of the population in radiation-toxically contaminated regions is systemic, including disturbances in the formation of hard dental tissues, congenital dental anomalies, and impaired immune defense with the manifestation of a decrease in local immunity, which causes a high prevalence of oral diseases. Practical significance: Standardization of the content of xenobiotics in various natural environments is carried out through a system for establishing maximum permissible concentrations (MAC) and maximum permissible levels (MAL). That if these permitted systems are violated, they can lead to various adverse environmental and hygienic consequences. Research prospects: This study presents the features of the influence of xenobiotic factors, which is an environmental and hygienic situation specific to the southern region of Kyrgyzstan. The special unfavorable nature of hygienic factors affects the population of the region.